Nasal comfort providing air-flow value in patients with seasonal allergic rhinitis

Radoslaw Spiewak

Source: Spiewak R. Nasal comfort providing air-flow value in patients with seasonal allergic rhinitis. Allergy 1998; 53 (Suppl 43: The Annual Meeting of the European Academy of Allergology and Clinical Immunology EAACI'98. Birmingham, UK, June 21-26, 1998): 166.

 

Objective: To assess the minimal nasal air-flow value, necessary to provide comfort of nasal breathing in patients with seasonal allergic rhinitis.

Patients: 125 subjects with seasonal allergic rhinitis aged 15-60 years and 30 healthy volunteers.

Methods: Measurement - anterior active rhinomanometry (Rhinotest MP-500) at differential (narichoanal) pressure 75 Pa. Data processing - Method 1: mathematical modelling of data distribution with AUC calculation. Method 2: self-developed software based on algorithms allowing to avoid errors of parametric statistics. Comparison of both methods used to find the predictive value.

Results: The minimal nasal comfort providing air-flow value computed according to the Method 1 was 379 cm3×s-1; and according to the Method 2: 308-314 cm3×s-1.

Conclusions: Analysis of data obtained in comparison to results of control group let me to propose a provisional system of interpreting rhinomanometry results in Polish population, where to date no population-oriented norms are available. This system might be helpful in case when clinical data are contradictory or not available. According to this system, total flow values higher that 390 cm3×s-1 might be considered as "normal", nasal flow of less than 280 cm3×s-1 - as "pathologic"; i.e. as limiting nasal comfort. The range 280-390 cm3×s-11 is an "area of uncertainty".

Related articles:

  1. Spiewak R, Brewczynski PZ. Rhinomanometrically controlled nasal provocation test: a comparison of results using this method in patients with seasonal allergic rhinitis and in healthy volunteers. Med Sci Monit 1998; 4 (1): 112-116.
  2. Spiewak R. Porownanie wynikow badania rynomanometrycznego z wybranymi objawami subiektywnymi i obiektywnymi u chorych na alergiczny niezyt nosa. Otolaryngol Pol 1998; 52 (1): 59-64. [Comparison of rhinomanometry results and selected subjective and objective symptoms in patients with seasonal allergic rhinitis (In Polish)].
  3. Spiewak R. Spor o miejsce rynomanometrii we wspolczesnej diagnostyce czynnosciowej gornych drog oddechowych. Otolaryngol Pol 1997; 51 (4): 377-383. [Comparison of rhinomanometry results and selected subjective and objective symptoms in patients with seasonal allergic rhinitis (In Polish)].
  4. Brewczynski PZ, Spiewak R, Galuszka-Ignasiak B, Dudek B, Bozek A, Maslowski T, Klin MJ. Zwiazek miedzy samopoczuciem a wynikami rinomanometrycznych pomiarow droznosci nosa u chorych na sezonowy niezyt nosa. Pneumonol Alergol Pol 1994; 62 (11-12): 578-582. [Correlation between symptoms and results of rhinomanometric measurements of nasal patency in patients with seasonal allergic rhinitis (In Polish)].
  5. Brewczynski PZ, Spiewak R, Galuszka B. Kliniczna i rinomanometryczna ocena skutecznosci flunizolidu w leczeniu alergicznego sezonowego niezytu nosa. Pneumonol Alergol Pol 1997; 51 (1-2): 84-89. [Clinical and rhinomanometric evaluation of flunisolide in treatment of seasonal allergic rhinitis (In Polish)].

Links:

Celimun - biomedical research outsourcing in allergy and immunology

ELISpot.biz - training and implementation

ELISpot.biz - scanning and analysis of ELISpot plates

immunologia.BIZ - odczynniki i aparatura: ELISpot, ELISA, cytometria

Celimun - badania biomedyczne na zlecenie

Institute of Dermatology, Krakow, Poland

Instytut Dermatologii w Krakowie

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This page is part of the www.RadoslawSpiewak.net website.
Document created: 23 November 2006, last updated: 23 November 2006.